The study examines the moderating influence of human resource practices on the relationship between emotional labour and wellbeing of Gen Y academicians. Data were collected from 314 Gen Y academicians from private universities in Malaysia and analyzed using the partial least squares structural equation model (PLS-SEM). The findings of the study show Gen Y academicians do experience emotional labour and employ both surface and deep acting at the workplace. More importantly the findings show that that there is positive and attributable human resource practices has a significant moderating effect on the relationship between emotional labour (Surface Acting & Deep Acting) and the wellbeing of the Gen Y academicians. Few studies to date have paid attention to the influence of human resource practices between emotional labour and wellbeing in the context of Gen Y workforce in an academic setting. The results of the study deserve attention of university management to better assist and support young academicians to manage their emotional health and as a result enhance their wellbeing at the workplace.