Biochemistry constitutes a fundamental biomedical science that forms the basis for dental pathophysiology, host–microbial interactions, pharmacotherapeutics, and general systemic–oral disease mechanisms. Although such knowledge has epistemological importance and significance, biochemistry appears to have a diminished presence in curricular visibility due to global shifts toward competency-based, patient-centered educational models and digitally enriched dental education. This paper conducts a comprehensive bibliometric analysis of trends in global biochemistry within dental education research from 1967 to 2025. A sample of 108 peer-reviewed publications indexed in Scopus, Web of Science, and PubMed was reviewed using Bibliometrix and VOSviewer. The performance indicators encompassed annual scientific output, citation metrics, authorship trends, h-index, g-index, and conceptual structure mapping through centrality density thematic analysis. The results show that the number of publication growth after 2015, coinciding with digital transformation and artificial intelligence integration in dental pedagogy. The United States and the United Kingdom have dominated productivity and citation impact, whereas developing regions are still underrepresented. The core themes cluster around “dental education,” “biochemistry,” and “education.” New clusters are forming around AI-assisted learning and adaptive assessment systems. This study offers strategic evidence for the modernization of curricula and the integration of digital technologies in biomedical dental education, particularly in emerging academic ecosystems such as Malaysia.