One of the side effect of technology advancement is the inability of nature to decompose substances created by human. Abundant waste of non-degradable plastic on land and oceans have become more increasingly serious issues. Therefore, there are growing research and development on natural-based materials with biodegradable properties. The interaction between biopolymer and nanofiller have attracted attentions for the improved functionality exhibit by them. The novel or improved characters are obtained depending on the type of nanofiller used such as antioxidant, antimicrobial properties, active agent and enhancement of mechanical and thermal properties. These features have great potential for the application in food packaging, medical and tissue engineering.