The number of children with disabilities, particularly learning disability, intellectual disability, and developmental disability have increased over the years. Raising children with disabilities can be challenging as it requires more effort, time, money, and energy. Low-income parents may face difficulties as they do not have adequate resources in managing the disabled children. This study examined low-income Muslim Malaysian parents’ struggles and challenges in caring for their disabled children. Data was obtained from face-to-face individual semi-structured interviews with seven parents. These parents were selected based on the following criteria set: (1) earning low-income; (2) having one child with disability; and (3) living in Klang Valley. Data was analysed using thematic analysis. This qualitative method approach was applied to generate seven major findings, namely, experiencing physical illnesses, financial constraints, emotional exhaustion, career setback, dealing with special child, dealing with spouse, and dealing with school. This research has the potential to inform the development of effective parental support programs, enhance awareness of the challenges faced by low-income Muslim Malaysian parents, and foster greater empathy toward families with disabilities.